Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Halfenprox SCHEMBL62803 | 0.91 | NPC1 (0.43) | NPC1POLBCYP2C9RAB9ATACR1 | |
| Halfenprox SCHEMBL29795788 | 0.91 | NPC1 (0.43) | NPC1POLBCYP2C9RAB9ATACR1 | |
| Halfenprox SCHEMBL28278482 | 0.89 | NPC1 (0.37) | NPC1POLBCYP2C9RAB9ATACR1 | |
| SCHEMBL10854916 | 0.85 | NPC1 (0.43) | NPC1POLBCYP2C9RAB9ATACR1 | |
| SCHEMBL7523252 | 0.84 | NPC1 (0.41) | NPC1POLBCYP2C9RAB9AFFAR1 | |
| SCHEMBL8675859 | 0.84 | MAPK14 (0.49) | NPC1POLBCYP2C9RAB9ATACR1 | |
| SCHEMBL8064118 | 0.84 | TACR1 (0.42) | NPC1POLBCYP2C9RAB9ATACR1 | |
| SCHEMBL10859391 | 0.82 | NPC1 (0.49) | NPC1POLBCYP2C9RAB9AFFAR1 | |
| SCHEMBL7524963 | 0.82 | FFAR1 (0.49) | NPC1POLBCYP2C9RAB9AFFAR1 | |
| SCHEMBL10849764 | 0.82 | NPC1 (0.41) | NPC1POLBCYP2C9RAB9ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205751-A1 | IMPROVED INSECT CONTROL STRATEGIES UTILIZING PHEROMONES AND RNAI | PROVIVI, INC. (US) | 2017-11-30 | — | — | WO | disclosed |