Halfenprox

Halfenprox

SCHEMBL28278482

CC(C)(COCc1cccc(Oc2ccccc2)c1)c1ccc(OC(F)(F)Br)cc1.c1ccc2nccnc2c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37
RAB9A P51151 1/20 0.37
FFAR1 O14842 6/20 0.36
FFAR4 Q5NUL3 2/20 0.36
MAPK14 Q16539 2/20 0.36
PPARG P37231 3/20 0.35
CETP P11597 2/20 0.35
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TACR1 P25103 1/20 0.34
TRPV6 Q9H1D0 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Halfenprox SCHEMBL62803 0.92 NPC1 (0.43) NPC1POLBCYP2C9RAB9AFFAR1
Halfenprox SCHEMBL29795788 0.92 NPC1 (0.43) NPC1POLBCYP2C9RAB9AFFAR1
Halfenprox SCHEMBL19643386 0.89 NPC1 (0.36) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL10854916 0.86 NPC1 (0.43) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL7523252 0.85 NPC1 (0.41) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL8064118 0.85 TACR1 (0.42) NPC1POLBCYP2C9RAB9AMAPK14
SCHEMBL8675859 0.85 MAPK14 (0.49) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL10859391 0.83 NPC1 (0.49) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL7524963 0.83 FFAR1 (0.49) NPC1POLBCYP2C9RAB9AFFAR1
SCHEMBL10849764 0.83 NPC1 (0.41) NPC1POLBCYP2C9RAB9AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109475493-A The method for preparing the formed body for animal to be administered 拜耳动物保健有限责任公司 2019-03-15 CN disclosed