Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.83 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.83 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967518 | 1.00 | MTNR1A (0.83) | MTNR1AMTNR1BSIGMAR1CCR8NPY5R | |
| SCHEMBL10324093 | 0.91 | MTNR1B (1.00) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL10324092 | 0.91 | MTNR1B (1.00) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL1966284 | 0.89 | MTNR1A (0.88) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL1966281 | 0.89 | MTNR1A (0.88) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL1966352 | 0.87 | MTNR1B (0.74) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL1966354 | 0.87 | MTNR1B (0.74) | MTNR1AMTNR1BSIGMAR1NPY5RLMNA | |
| SCHEMBL1965039 | 0.87 | MTNR1A (0.70) | MTNR1AMTNR1BNPY5RLMNATP53 | |
| SCHEMBL1965037 | 0.87 | MTNR1A (0.70) | MTNR1AMTNR1BNPY5RLMNATP53 | |
| SCHEMBL1965540 | 0.86 | MTNR1A (0.73) | MTNR1AMTNR1BSIGMAR1NPY5RTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2012-07-19 | — | — | US | claimed |
| EP-2203422-B1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INT (ES) | 2011-06-22 | — | — | EP | claimed |
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2012-07-19 | — | — | US | disclosed |
| EP-2203422-B1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INT (ES) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | MTNR1A, MTNR1B, MC4R | MTNR1A 1/4885MTNR1B 2/4885SIGMAR1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.