Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 11/20 | 0.37 |
| ▸ | NPY1R | P25929 | 6/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475812 | 1.00 | NOS3 (0.38) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL27382578 | 0.84 | NOS3 (0.41) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL9952947 | 0.84 | NOS3 (0.41) | NOS3NOS1NOS2NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL8063762 | 0.83 | NOS3 (0.41) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL2172217 | 0.80 | NPY4R (0.45) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL42488 | 0.80 | NPY4R (0.45) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL157856 | 0.80 | NPY4R (0.45) | NOS3NOS1NOS2NPY4RNPY1R | |
| SCHEMBL18796571 | 0.79 | DPP7 (0.41) | NOS3NOS1NOS2NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL2762373 | 0.78 | NPY4R (0.44) | NOS3NOS1NOS2NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL940539 | 0.78 | NPY4R (0.44) | NOS3NOS1NOS2NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556068-A | CD44 binding peptide reagents and methods | 密歇根大学董事会 | 2024-08-27 | — | — | CN | disclosed |
| CN-110831634-B | Glypican-3 peptide reagents and methods | 密歇根大学董事会 | 2024-07-02 | — | — | CN | disclosed |
| CN-112546244-B | Fibroblast growth factor receptor 2 specific peptide reagents and methods | 密执安州立大学董事会 | 2023-07-04 | — | — | CN | disclosed |
| CN-108697756-B | HER2 peptide reagents and methods | 密歇根大学董事会 | 2022-05-27 | — | — | CN | disclosed |
| CN-114269367-A | Therapeutic peptides | 科巴公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113518784-A | Therapeutic peptides | 科巴公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-107073065-B | Peptide reagents and methods for detection and targeting of dysplasia, early stage cancer, and cancer | 密歇根大学董事会 | 2021-07-02 | — | — | CN | disclosed |
| CN-112546244-A | Fibroblast growth factor receptor2 specific peptide reagents and methods | 密执安州立大学董事会 | 2021-03-26 | — | — | CN | disclosed |
| CN-111107881-A | Fibroblast growth factor receptor2 specific peptide reagents and methods | 密执安州立大学董事会 | 2020-05-05 | — | — | CN | disclosed |
| CN-110831634-A | Glypican-3 peptide reagents and methods | 密歇根大学董事会 | 2020-02-21 | — | — | CN | disclosed |
| CN-105324397-B | Insulin-incretin conjugates | 印第安纳大学研究及科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| EP-3463429-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | Merck Sharp & Dohme Corp. (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017205191-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |