Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852653 | 0.74 | ALDH1A1 (0.48) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL11630480 | 0.72 | TDP1 (0.54) | TDP1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL8999606 | 0.69 | ALDH1A1 (0.42) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL8999712 | 0.68 | SELL (0.55) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL9771322 | 0.68 | TDP1 (0.42) | TDP1KMT2AACHECYP3A4MEN1 | |
| SCHEMBL16298959 | 0.67 | ALDH1A1 (0.39) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL3182711 | 0.66 | SELL (0.52) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL68928 | 0.66 | TDP1 (0.67) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL9579926 | 0.66 | SELL (0.52) | TDP1ALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL28417825 | 0.66 | TDP1 (0.46) | TDP1ALDH1A1KMT2AGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | disclosed |