SCHEMBL8999712

SCHEMBL8999712

Cc1cc(O)c(Cc2c(O)cc(C)cc2O)c(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.55
SELP P16109 1/20 0.55
SELE P16581 1/20 0.55
ACHE P22303 1/20 0.55
TRPA1 O75762 2/20 0.43
ALDH1A1 P00352 3/20 0.43
AMY1A P0DUB6 1/20 0.41
PTPN1 P18031 1/20 0.41
BACE1 P56817 1/20 0.41
DAO P14920 1/20 0.41
POLB P06746 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
APEX1 P27695 1/20 0.39
MPI P34949 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69436 0.87 SELL (0.48) SELLSELPSELEACHETRPA1
SCHEMBL8999606 0.84 ALDH1A1 (0.42) SELLSELPSELEACHETRPA1
SCHEMBL9579926 0.80 SELL (0.52) SELLSELPSELEACHETRPA1
SCHEMBL3182711 0.80 SELL (0.52) SELLSELPSELEACHETRPA1
SCHEMBL8376741 0.79 SELL (0.46) SELLSELPSELEACHETRPA1
SCHEMBL3977821 0.79 ALDH1A1 (0.56) SELLSELPSELEACHEALDH1A1
SCHEMBL31545719 0.78 SELL (0.50) SELLSELPSELEACHETRPA1
SCHEMBL9743217 0.76 HTT (0.56) SELLSELPSELEACHETRPA1
SCHEMBL12599519 0.75 SLC28A3 (0.44) ACHEALDH1A1BACE1POLBMAPT
SCHEMBL6847133 0.74 AMY1A (0.55) SELLSELPSELEACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8231367-A None JP disclosed
JP-H08231367-A TYROSINASE ACTIVITY INHIBITOR NIPPON PAINT CO LTD 1996-09-10 JP disclosed