Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823282 | 1.00 | SMPD1 (0.39) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL19387369 | 0.98 | SMPD1 (0.38) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL19687899 | 0.92 | SMPD1 (0.37) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL13735176 | 0.89 | SMPD1 (0.33) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL24027192 | 0.88 | OPRM1 (0.34) | SMPD1FDPSALDH1A1 | |
| SCHEMBL21230013 | 0.87 | FDPS (0.33) | FDPSALDH1A1 | |
| SCHEMBL12159929 | 0.76 | OPRM1 (0.41) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL13960425 | 0.74 | OPRM1 (0.39) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL19557514 | 0.74 | OPRM1 (0.39) | SMPD1FDPSDNM1MEN1KMT2A | |
| SCHEMBL18823471 | 0.74 | OPRM1 (0.39) | SMPD1FDPSDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |