Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261514 | 0.99 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645492 | 0.97 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261485 | 0.96 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645484 | 0.94 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261519 | 0.94 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261530 | 0.93 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioforminol SCHEMBL374830 | 0.93 | LMNA (0.65) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261524 | 0.93 | LMNA (0.53) | LMNACYP2C19HIF1A | |
| SCHEMBL21727971 | 0.92 | LMNA (0.72) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261490 | 0.91 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827334-B2 | Preparation of ioforminol, an x-ray contrast agent | GE HEALTHCARE AS (NO) | 2017-11-28 | — | — | US | disclosed |