Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261523 | 0.97 | LMNA (0.74) | LMNACYP2C19HIF1A | |
| SCHEMBL2763800 | 0.92 | LMNA (0.83) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645487 | 0.92 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19261514 | 0.91 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645492 | 0.91 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10329899 | 0.91 | LMNA (0.88) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20350848 | 0.90 | LMNA (0.86) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20034186 | 0.90 | LMNA (0.82) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL14601670 | 0.90 | CYP2C19 (0.86) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL16202566 | 0.89 | LMNA (0.78) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793951-B1 | STABILIZATION OF X-RAY DIAGNOSTIC COMPOSITION | GE HEALTHCARE AS (NO) | 2020-02-19 | — | — | EP | disclosed |