Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770800 | 0.74 | GAA (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28577615 | 0.73 | GAA (0.59) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL18495722 | 0.71 | CA2 (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5865439 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2499107 | 0.69 | GAA (0.48) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL12306892 | 0.68 | ALDH1A1 (0.87) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL13783355 | 0.68 | GAA (0.52) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL2493552 | 0.66 | GAA (0.50) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL6547519 | 0.66 | GAA (0.50) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL28433392 | 0.65 | CA2 (0.60) | ALDH1A1SMN1; SMN2HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828396-B2 | Alkyne compounds for treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |