SCHEMBL19646153

SCHEMBL19646153

Cc1cc(OCc2c(F)cccc2-n2nnn(C)c2=O)c(C)cc1O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 2/20 0.37
MRGPRX4 Q96LA9 2/20 0.36
MAPT P10636 1/20 0.32
RAB9A P51151 2/20 0.32
ALKBH1 Q13686 1/20 0.32
NPC1 O15118 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GUCY1B2 O75343 4/20 0.31
GUCY1A2 P33402 4/20 0.31
GUCY1A1 Q02108 4/20 0.31
GUCY1B1 Q02153 4/20 0.31
SLC22A12 Q96S37 1/20 0.31
ROCK2 O75116 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16920796 0.92 PTGER1 (0.37) PTGER1MRGPRX4MAPTRAB9ANPC1
SCHEMBL19646240 0.91 MAPT (0.37) PTGER1MAPTRAB9AALDH1A1
SCHEMBL19646115 0.91 MAPT (0.37) PTGER1MRGPRX4MAPTRAB9AALKBH1
SCHEMBL16442873 0.91 SLC22A12 (0.37) PTGER1MRGPRX4MAPTRAB9ASLC22A12
SCHEMBL15851139 0.89 PTGER1 (0.39) PTGER1MRGPRX4MAPT
SCHEMBL19646111 0.88 HSP90AA1 (0.33) MRGPRX4MAPTRAB9ASLC22A12
SCHEMBL19646109 0.88 ATP4A (0.34) MRGPRX4MAPTSMN1; SMN2SLC22A12
SCHEMBL19646118 0.88 MRGPRX4 (0.35) MRGPRX4MAPTRAB9ASLC22A12
SCHEMBL19646220 0.88 PTGER1 (0.32) PTGER1MRGPRX4MAPTRAB9ASLC22A12
SCHEMBL19646166 0.88 MAPT (0.35) MRGPRX4MAPTSMN1; SMN2SLC22A12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed