SCHEMBL19646115

SCHEMBL19646115

Cc1cc(O)c(Cl)cc1OCc1c(F)cccc1-n1nnn(C)c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
RAB9A P51151 1/20 0.36
PTGER1 P34995 2/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
KMT2A Q03164 2/20 0.34
MAPK14 Q16539 1/20 0.34
ALDH1A1 P00352 3/20 0.34
ALKBH1 Q13686 1/20 0.34
SGMS2 Q8NHU3 1/20 0.33
COMT P21964 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DHODH Q02127 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19646152 0.92 RAB9A (0.37) MAPTRAB9APTGER1MRGPRX4KMT2A
SCHEMBL19646217 0.91 MRGPRX4 (0.35) MAPTMRGPRX4BDKRB2
SCHEMBL16920800 0.91 MAPT (0.38) MAPTRAB9APTGER1MRGPRX4KMT2A
SCHEMBL19646233 0.91 SLC22A12 (0.35) MRGPRX4NPSR1BDKRB2
SCHEMBL19646153 0.91 PTGER1 (0.37) MAPTRAB9APTGER1MRGPRX4ALDH1A1
SCHEMBL19646240 0.89 MAPT (0.37) MAPTRAB9APTGER1KMT2AMAPK14
SCHEMBL19646189 0.89 MRGPRX4 (0.35) PTGER1MRGPRX4BDKRB2
SCHEMBL19646168 0.89 BDKRB2 (0.34) MAPTMRGPRX4ALDH1A1HTTL3MBTL1
SCHEMBL19646193 0.89 BDKRB2 (0.33) PTGER1MRGPRX4MAPK14BDKRB2
SCHEMBL19646191 0.89 ADCYAP1R1 (0.35) MAPTKMT2AALDH1A1MEN1BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed