Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19309204 | 0.86 | BRS3 (0.40) | CTSSCTSKBRS3SOS2GABRA5 | |
| SCHEMBL24608472 | 0.81 | SOS2 (0.38) | CTSSCTSKBRS3SOS2GABRA5 | |
| SCHEMBL18649327 | 0.79 | SOS2 (0.33) | CTSSSOS2 | |
| SCHEMBL2960222 | 0.78 | CTSK (0.41) | CTSSCTSKBRS3SOS2EGLN2 | |
| SCHEMBL14407566 | 0.77 | HMGCR (0.35) | — | |
| SCHEMBL18896469 | 0.77 | HMGCR (0.40) | — | |
| SCHEMBL1111352 | 0.75 | CTSK (0.39) | CTSSCTSKBRS3SOS2EGLN2 | |
| SCHEMBL19503987 | 0.75 | CCR1 (0.40) | — | |
| SCHEMBL24794162 | 0.75 | CTSS (0.49) | CTSSCTSKSOS2SRCIRAK4 | |
| SCHEMBL19091157 | 0.74 | BRS3 (0.30) | CTSSBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828377-B2 | Heterocyclic compounds and uses thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |