Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.64 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739326 | 0.80 | HCAR2 (1.00) | HCAR2HCAR3NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL31467457 | 0.79 | HCAR2 (0.96) | HCAR2HCAR3NPC1RAB9AMAPT | |
| SCHEMBL21401472 | 0.78 | HCAR3 (0.60) | HCAR2HCAR3MMENPC1RAB9A | |
| SCHEMBL19646367 | 0.73 | HCAR3 (0.66) | HCAR2HCAR3MMENPC1RAB9A | |
| SCHEMBL21401431 | 0.71 | HCAR3 (0.64) | HCAR2HCAR3MMENPC1RAB9A | |
| SCHEMBL5599627 | 0.69 | HCAR2 (0.76) | HCAR2HCAR3MMEKDM5ADAO | |
| SCHEMBL26784594 | 0.69 | HCAR3 (0.59) | HCAR2HCAR3MMENPC1RAB9A | |
| SCHEMBL15253861 | 0.69 | HCAR3 (0.75) | HCAR2HCAR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5599520 | 0.68 | HCAR2 (0.69) | HCAR2HCAR3DAO | |
| SCHEMBL5599868 | 0.68 | HCAR2 (0.69) | HCAR2HCAR3DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828370-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |