Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.66 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26450032 | 0.88 | HCAR3 (0.50) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21401431 | 0.84 | HCAR3 (0.64) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21401472 | 0.81 | HCAR3 (0.60) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15253861 | 0.81 | HCAR3 (0.75) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15116888 | 0.79 | HCAR3 (0.72) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1739326 | 0.79 | HCAR2 (1.00) | HCAR3HCAR2NPC1RAB9ALMNA | |
| SCHEMBL31088685 | 0.79 | HCAR3 (0.66) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19924463 | 0.78 | HCAR3 (0.70) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31467457 | 0.78 | HCAR2 (0.96) | HCAR3HCAR2NPC1RAB9ALMNA | |
| SCHEMBL26784594 | 0.78 | HCAR3 (0.59) | HCAR3HCAR2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725005-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-10906896-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200031819-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2020-01-30 | — | — | US | disclosed |
| US-10344027-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-10316031-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20190119266-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2019-04-25 | — | — | US | disclosed |
| US-20190055234-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2019-02-21 | — | — | US | disclosed |
| US-10005740-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-06-26 | — | — | US | disclosed |
| US-9828370-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316031-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-10344027-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-20190119266-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-20190055234-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-10005740-B2 | Neprilysin inhibitors | MME, REN, AGTR1 | HCAR3 1155/4885HCAR2 2251/4885NPC1 158/4885 |
| US-20200031819-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-10906896-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
| US-11725005-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | HCAR3 3241/4885HCAR2 4221/4885NPC1 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.