Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956768 | 0.88 | PTGER4 (0.54) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL28484982 | 0.88 | PTGER4 (0.54) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL196468 | 0.83 | SRD5A2 (0.44) | PTGER4PTGER2SRD5A2PTGDR | |
| SCHEMBL23089018 | 0.83 | PTGER4 (0.49) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL23089016 | 0.83 | PTGER4 (0.49) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL28474778 | 0.81 | PTGER4 (0.42) | PTGER4PTGER2SRD5A2PTGDRPTGER3 | |
| SCHEMBL28474779 | 0.80 | SRD5A2 (0.43) | PTGER4PTGER2SRD5A2PTGER3 | |
| SCHEMBL1956758 | 0.78 | PTGER4 (0.56) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL253776 | 0.78 | PTGER4 (0.54) | PTGER4PTGER2SRD5A2PTGDRPTGER3 | |
| SCHEMBL28477223 | 0.78 | PTGER4 (0.56) | PTGER4PTGER2PTGDRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500211-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2320906-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS | Beta Pharma Canada Inc. (CA) | 2011-05-18 | — | — | EP | claimed |
| WO-2010019796-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS | CHEMIETEK, LLC (US) | 2010-02-18 | — | — | WO | claimed |