SCHEMBL23089016

SCHEMBL23089016

CC(C)(NC(=O)c1cc(F)cc2ccc(Cc3ccc(C(F)(F)F)cc3)n12)c1ccc(C(=O)O)cc1.C[C@H](NC(=O)c1cc(F)cc2ccc(Cc3ccc(C(F)(F)F)cc3)n12)c1ccc(C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.49
PTGER2 P43116 1/20 0.49
PTGDR Q13258 2/20 0.46
PTGER3 P43115 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23089018 1.00 PTGER4 (0.49) PTGER4PTGER2PTGDRPTGER3
SCHEMBL28484982 0.94 PTGER4 (0.54) PTGER4PTGER2PTGDRPTGER3
SCHEMBL1956768 0.94 PTGER4 (0.54) PTGER4PTGER2PTGDRPTGER3
SCHEMBL23089017 0.92 PDE2A (0.41) PTGER4PTGER2PTGDRPTGER3
SCHEMBL196468 0.92 SRD5A2 (0.44) PTGER4PTGER2PTGDR
SCHEMBL1956758 0.85 PTGER4 (0.56) PTGER4PTGER2PTGDRPTGER3
SCHEMBL28477223 0.85 PTGER4 (0.56) PTGER4PTGER2PTGDRPTGER3
SCHEMBL196469 0.83 PTGER4 (0.43) PTGER4PTGER2PTGDRPTGER3
SCHEMBL28474778 0.81 PTGER4 (0.42) PTGER4PTGER2PTGDRPTGER3
SCHEMBL28474779 0.80 SRD5A2 (0.43) PTGER4PTGER2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210079013-A1 Heterobicyclic Carboxylic Acids and Salts Thereof SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) 2021-03-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079013-A1 Heterobicyclic Carboxylic Acids and Salts Thereof PTGER4, PTGER1, GPR4 PTGER4 1/4885PTGER2 9/4885PTGDR 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.