Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366724 | 0.80 | MAP3K14 (0.59) | MAP3K14HTR1ACYP2D6SLC6A4LTB4R | |
| SCHEMBL4751498 | 0.80 | MAP3K14 (0.59) | MAP3K14KDM4CHTR1ACYP2D6SLC6A4 | |
| SCHEMBL15825637 | 0.80 | KDM4C (0.52) | MAP3K14KDM4CHTR1ASLC6A4GPR84 | |
| SCHEMBL8773430 | 0.73 | HTR1A (0.51) | MAP3K14HTR1ACYP2D6SLC6A4 | |
| SCHEMBL14183091 | 0.73 | MAP3K14 (0.67) | MAP3K14 | |
| SCHEMBL1111009 | 0.73 | MAP3K14 (0.67) | MAP3K14 | |
| SCHEMBL13614279 | 0.72 | MAP3K14 (0.50) | MAP3K14HTR1ACYP2D6SLC6A4 | |
| SCHEMBL8773445 | 0.72 | HTR1A (0.50) | MAP3K14KDM4CHTR1ACYP2D6SLC6A4 | |
| SCHEMBL3556913 | 0.71 | MAP3K14 (0.65) | MAP3K14KDM4CHTR1A | |
| SCHEMBL22143947 | 0.71 | MAP3K14 (0.65) | MAP3K14KDM4CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828343-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-11-28 | — | — | US | disclosed |