Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | IL2RA | P01589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18912329 | 1.00 | GAA (0.54) | GAACYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL22810961 | 0.93 | POLB (0.49) | GAAALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL2734908 | 0.93 | POLB (0.49) | GAAALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL9892967 | 0.93 | POLB (0.49) | GAAALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL21699252 | 0.93 | POLB (0.49) | GAAALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL15313443 | 0.93 | POLB (0.49) | GAAALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL20196522 | 0.89 | GAA (0.42) | GAACYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL23209735 | 0.89 | ATM (0.54) | GAACYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL23209734 | 0.89 | ATM (0.54) | GAACYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL2755697 | 0.89 | ATM (0.54) | GAACYP2C9CYP2C19ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-2780039-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2017-11-29 | — | — | EP | disclosed |