SCHEMBL19647328

SCHEMBL19647328

C[C@@]1(C=O)CCCN1C(=O)CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.44
JAK3 P52333 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968635 0.75 MGLL (0.37) MGLL
SCHEMBL17739917 0.74 MGLL (0.59) MGLL
SCHEMBL19703587 0.71 MGLL (0.54) MGLL
SCHEMBL19703601 0.70 MGLL (0.49) MGLL
SCHEMBL20196740 0.70 MGLL (0.49) MGLL
SCHEMBL17739988 0.70 MGLL (0.49) MGLL
SCHEMBL17740198 0.70 MGLL (0.49) MGLL
SCHEMBL19698198 0.70 MGLL (0.49) MGLL
SCHEMBL19703600 0.69 MGLL (0.51) MGLL
SCHEMBL19703726 0.69 MGLL (0.51) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780039-B9 CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF PFIZER (US) 2018-04-18 EP disclosed
EP-2780039-B1 CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF PFIZER (US) 2017-11-29 EP disclosed