Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185086 | 0.95 | KMT2A (0.40) | KMT2AALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL184992 | 0.89 | CA12 (0.40) | KMT2AALDH1A1HSD17B10TDP1SLC6A3 | |
| SCHEMBL2363042 | 0.79 | PTGS1 (0.55) | KMT2APTGS1PTGS2MEN1CA2 | |
| SCHEMBL1550706 | 0.75 | ENPP2 (0.42) | KMT2ACYP3A4MEN1CA2CA12 | |
| SCHEMBL184810 | 0.75 | CA12 (0.43) | KMT2AALDH1A1CA2CA12CA1 | |
| SCHEMBL184847 | 0.74 | SMN1; SMN2 (0.52) | KMT2AALDH1A1MEN1SMN1; SMN2GAA | |
| SCHEMBL661853 | 0.74 | KMT2A (0.48) | KMT2APTGS1PTGS2MEN1NPC1 | |
| SCHEMBL30474572 | 0.74 | KMT2A (0.48) | KMT2APTGS1PTGS2MEN1NPC1 | |
| SCHEMBL68152 | 0.73 | KMT2A (0.64) | KMT2AALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL319987 | 0.73 | KMT2A (0.64) | KMT2AALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |