Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19648567 | 0.97 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL19648699 | 0.84 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19648691 | 0.83 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL19648585 | 0.82 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL19648530 | 0.80 | LMNA (0.35) | MAPTSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19648544 | 0.79 | LMNA (0.34) | MAPTSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19648563 | 0.78 | NPC1 (0.31) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19648572 | 0.78 | NPC1 (0.30) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19648698 | 0.77 | — | — | |
| SCHEMBL19648715 | 0.76 | MAPT (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |