Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19648934 | 0.99 | KMT2A (0.36) | LMNASMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL19648537 | 0.99 | LMNA (0.34) | LMNASMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL19648538 | 0.91 | LMNA (0.38) | LMNAKMT2AMEN1MAPK1MAPT | |
| SCHEMBL19648536 | 0.91 | LMNA (0.37) | LMNASMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL19648576 | 0.87 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL19648923 | 0.84 | HSP90AA1 (0.31) | — | |
| SCHEMBL19648737 | 0.84 | L3MBTL1 (0.35) | KMT2AMEN1MAPK1MAPT | |
| SCHEMBL19648530 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL19648730 | 0.83 | MAPT (0.39) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL19648544 | 0.83 | LMNA (0.34) | LMNASMN1; SMN2KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |