Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573108 | 0.85 | SIGMAR1 (0.33) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL19648885 | 0.82 | BCHE (0.35) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5519960 | 0.77 | PARP10 (0.44) | MGLLPOLBCA1CA2MAPT | |
| SCHEMBL12817707 | 0.73 | POLB (0.42) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL4793606 | 0.70 | HTR3E (0.59) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL16573109 | 0.70 | KMT2A (0.32) | HSD17B10MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16570142 | 0.69 | TDP1 (0.35) | POLBHSD17B10MAPTRAB9AKMT2A | |
| SCHEMBL11504114 | 0.68 | HTR3E (0.61) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL15993007 | 0.67 | POLB (0.43) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL2925759 | 0.65 | HTR3E (0.68) | SIGMAR1HTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848669-B1 | Electrochromic composition | ESSILOR INT (COMPAGNIE GÉNÉRALE D'OPTIQUE) (FR) | 2017-11-29 | — | — | EP | disclosed |