Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 17/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506665 | 0.84 | LMNA (0.59) | PTPRBALDH1A1LMNAHPGDSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL7639969 | 0.82 | SLC7A5 (0.41) | — | |
| SCHEMBL6143035 | 0.77 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAALDH1A1 | |
| SCHEMBL4455223 | 0.76 | PTPRB (0.48) | PTPRBPTPN2PTPN1PTPRAALDH1A1 | |
| SCHEMBL6575823 | 0.76 | TAAR1 (0.48) | — | |
| SCHEMBL27546590 | 0.74 | HTR6 (0.60) | PTPRBPTPN2PTPN1PTPRAALDH1A1 | |
| SCHEMBL19649501 | 0.74 | PTPRB (0.45) | PTPRB | |
| SCHEMBL23752204 | 0.73 | HPGD (0.61) | PTPRBPTPN2PTPN1PTPRAALDH1A1 | |
| SCHEMBL4021109 | 0.73 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAALDH1A1 | |
| SCHEMBL6143034 | 0.73 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044151-A | Sulfamidophenethanolamine therapeutic process | MEAD JOHNSON & COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4044151-A | Sulfamidophenethanolamine therapeutic process | MEAD JOHNSON & COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4044151-A | Sulfamidophenethanolamine therapeutic process | MEAD JOHNSON & COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3923886-A | Sulfamides | MEAD JOHNSON & CO | 1975-12-02 | — | — | US | disclosed |