Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13336029 | 0.84 | ACHE (0.39) | HTR2AHTR2BHTR2CTAAR1 | |
| SCHEMBL14259218 | 0.81 | HTR2A (0.33) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL21028524 | 0.78 | ACP3 (0.47) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL13362473 | 0.77 | TP53 (0.41) | IDO1MAPTSIGMAR1LMNAKDM4E | |
| SCHEMBL46757 | 0.77 | HTR2A (0.63) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL776678 | 0.76 | TAAR1 (0.47) | TAAR1IDO1MIFMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL266843 | 0.75 | HTR2A (0.61) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL9626024 | 0.74 | TAAR1 (0.44) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL5103155 | 0.74 | TAAR1 (0.64) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL3237564 | 0.74 | TAAR1 (0.64) | HTR2AHTR2BHTR2CTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | disclosed |