SCHEMBL196503

SCHEMBL196503

C[Si](C)(C)c1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
CYP2A6 P11509 1/20 0.50
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
IDO1 P14902 2/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ADRB2 P07550 1/20 0.36
NOTUM Q6P988 4/20 0.36
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
CYP19A1 P11511 1/20 0.33
ENPP2 Q13822 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586534 0.83 NR1H2 (0.50) NR1H2NR1H3
SCHEMBL11744841 0.82 SRD5A2 (0.57) LMNATSHRALDH1A1CES2CES1
Chlorobenzene SCHEMBL29067378 0.80 TSHR (0.58) LMNACYP2A6NR1H2NR1H3IDO1
SCHEMBL7913246 0.79 LMNA (0.47) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL20455818 0.79 LMNA (0.47) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL6477550 0.79 LMNA (0.47) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL2921010 0.77 LMNA (0.44) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL10790524 0.77 LMNA (0.44) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL3410663 0.77 LMNA (0.44) LMNACYP2A6IDO1MEN1KMT2A
SCHEMBL12817291 0.75 NR1H2 (0.41) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108164692-B Silicon modified polyether and preparation method and application thereof 上海东大化学有限公司 2020-02-07 CN claimed
CN-108166250-B Scouring agent and preparation method and application thereof 上海东大化学有限公司 2020-02-07 CN claimed
CN-108166257-B Mercerizing penetrating agent and preparation method thereof 上海东大化学有限公司 2019-12-31 CN claimed
EP-4665738-A1 MIXED P,N-DONOR LIGANDS, THEIR COMPLEXES AND USE THEREOF Umicore AG & Co. KG (DE) 2025-12-24 EP disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
WO-2024179773-A1 MIXED P,N-DONOR LIGANDS, THEIR COMPLEXES AND USE THEREOF UMICORE AG & CO. KG (DE) 2024-09-06 WO disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
CN-116554066-A Method for synthesizing N- (hetero) aryl sulfonamide compound 陕西师范大学 2023-08-08 CN disclosed
CN-116444483-A Preparation method of 1,3-dithiane substituted diene derivative 兰州大学 2023-07-18 CN disclosed
US-11614686-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-28 US disclosed
EP-0133012-B1 A SHEET FOR USE IN HEAT TRANSFER PRINTING DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1990-03-14 EP disclosed
US-4820687-A MOLD RELEASABILITY, HIGH DENSITY DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1989-04-11 US disclosed
EP-0296878-A2 Modified polysiloxane-coated sanitary rubber article and process for its production DAIKYO GOMU SEIKO LTD. (JP) 1988-12-28 EP disclosed
US-4694039-A Stabilized lactam polymerization solutions DSM RIM NYLON V.O.F. (NL) 1987-09-15 US disclosed
US-4672085-A LACTAM SUBSTITUTED POLYBUTADIENE INITIATOR,TRISUBTITED UREA STABILIZER;NYLON BLOCK COPOLYMERS DSM RIM NYLON VOF (NL) 1987-06-09 US disclosed
US-4626256-A PRODUCT OF AMINO-MODIFIDE SILICON AND EPOXY-MODIFIED SILICONE DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1986-12-02 US disclosed
US-4555427-A RECEPTIVE LAYER HAS TWO REGIONS OF DIFFERING GLASS TRANSISTION TEMPERATURES DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1985-11-26 US disclosed
EP-0133011-A2 A sheet for use in heat transfer printing DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1985-02-13 EP disclosed
US-4042613-A PHOTOSENSITIZERS, POLYMERS DAI NIPPON PRINTING CO., LTD. (JA) 1977-08-16 US disclosed