SCHEMBL586534

SCHEMBL586534

C[Si](C)(C)c1ccc([Si](C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
ESR1 P03372 2/20 0.35
ESR2 Q92731 1/20 0.35
HPGD P15428 1/20 0.35
ACHE P22303 1/20 0.34
SCN5A Q14524 1/20 0.34
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10997473 0.89 NR1H2 (0.44) NR1H2NR1H3ESR1ESR2HPGD
SCHEMBL987122 0.86 ACHE (0.53) NR1H2NR1H3HPGDACHE
SCHEMBL196503 0.83 LMNA (0.50) NR1H2NR1H3
SCHEMBL8932050 0.83 NR1H2 (0.46) NR1H2NR1H3ACHESCN5A
SCHEMBL1172568 0.83 MEN1 (0.50) NR1H2NR1H3ACHE
SCHEMBL23612702 0.83 NR1H2 (0.48) NR1H2NR1H3
SCHEMBL11979357 0.83 NR1H2 (0.46) NR1H2NR1H3ESR1ESR2HPGD
SCHEMBL17492039 0.83 NR1H2 (0.41) NR1H2NR1H3
SCHEMBL570229 0.83 CYP2A6 (0.50) NR1H2NR1H3HPGDGAA
SCHEMBL6512153 0.83 NR1H2 (0.41) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360549-A1 LOW-TEMPERATURE DEPOSITION PROCESSES TO FORM MOLYBDENUM-BASED MATERIALS WITH IMPROVED RESISTIVITY APPLIED MATERIALS, INC. 2024-10-31 US claimed
WO-2024226669-A1 LOW-TEMPERATURE DEPOSITION PROCESSES TO FORM MOLYBDENUM-BASED MATERIALS WITH IMPROVED RESISTIVITY APPLIED MATERIALS, INC. (US) 2024-10-31 WO claimed
CN-118530564-A PET/PBT resin composition and preparation method thereof 广东中塑新材料股份有限公司 2024-08-23 CN claimed
CN-118359904-A Flame retardant PET composition and preparation method thereof 广东中塑新材料股份有限公司 2024-07-19 CN claimed
CN-117343638-A Porous spin-on dielectric coating materials from silicon-containing polymers 上海艾深斯科技有限公司 2024-01-05 CN claimed
CN-114231010-B Invisible optical cable 马鞍山新地优特威光纤光缆有限公司 2023-09-08 CN claimed
CN-114231010-A Invisible optical cable 马鞍山新地优特威光纤光缆有限公司 2022-03-25 CN claimed
US-9335388-B2 Reference material for NMR, sample tube for NMR, capillary for NMR, and method for measuring NMR for a sample SHISEIDO COMPANY, LTD. (JP) 2016-05-10 US claimed
EP-2752677-B1 Sample tube for NMR measurements SHISEIDO CO LTD (JP) 2015-07-22 EP claimed
EP-2752677-A1 Sample tube for NMR measurements Shiseido Company, Ltd. (JP) 2014-07-09 EP claimed
EP-2007703-B1 METAL COMPLEXES FOR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS LUCITE INT UK LTD (GB) 2013-12-18 EP claimed
US-20120313644-A1 REFERENCE MATERIAL FOR NMR, SAMPLE TUBE FOR NMR, CAPILLARY FOR NMR, AND METHOD FOR MEASURING NMR FOR A SAMPLE SHISEIDO COMPANY, LTD. (JP) 2012-12-13 US claimed
EP-2523010-A1 REFERENCE MATERIAL FOR NMR, SAMPLE TUBE FOR NMR, CAPILLARY FOR NMR, AND METHOD FOR DETERMINING NMR SPECTRUM OF SAMPLE Shiseido Company, Ltd. (JP) 2012-11-14 EP claimed
US-6294482-B1 Method of forming an insulating layer pattern in a liquid crystal display LG LCD INC. (KR) 2001-09-25 US claimed
US-6156692-A Ruthenium-containing catalyst composition for olefin metathesis BP AMOCO CORPORATION (US) 2000-12-05 US claimed
US-6060130-A FORMING AN ORGANIC SILICON-CONTAINING FILM ON AN INSULATING SUBSTRATE, PROVIDING AN OXIDIZING ATMOSPHERE, IRRADIATING TO GENERATE SILICON(SI) AND OXYGEN(O) RADICALS, AND FORMING SILICON OXIDE INSULATING FILM BY REACTING SI AND O RADICALS LG ELECTRONICS INC. (KR) 2000-05-09 US claimed
EP-0251408-A1 Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation THE PROCTER & GAMBLE COMPANY (US) 1988-01-07 EP claimed
US-20260139119-A1 RECYCLING METHOD FOR POLYAMIDES AND COMPOSITES EAGAN JAMES (US) 2026-05-21 US disclosed
EP-0251408-A1 Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation THE PROCTER & GAMBLE COMPANY (US) 1988-01-07 EP disclosed
US-4513137-A Iodonium salts THE UNIVERSITY OF AKRON (US) 1985-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139119-A1 RECYCLING METHOD FOR POLYAMIDES AND COMPOSITES TRDMT1, PARG, WDR5 NR1H2 3062/4885NR1H3 2733/4885ESR1 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.