Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.60 |
| ▸ | WDR5 | P61964 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067414 | 0.86 | MAPT (0.69) | MYCWDR5ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9548025 | 0.84 | KDM4E (0.67) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL558439 | 0.84 | ALDH1A1 (0.68) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL19638079 | 0.83 | MYC (0.57) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL19638014 | 0.83 | MYC (0.57) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL25804366 | 0.80 | ALDH1A1 (0.72) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL20767251 | 0.80 | ALDH1A1 (0.67) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL16669665 | 0.80 | ALDH1A1 (0.75) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL10120487 | 0.79 | KDM4E (0.59) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL7050538 | 0.79 | MAPT (0.59) | MYCWDR5ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248964-A1 | THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS | PALOBIOFARMA S.L. (ES) | 2017-11-29 | — | — | EP | disclosed |