Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725429 | 0.95 | CYP11B1 (0.41) | CYP11B1NISCHALOX5NT5ECYP1A1 | |
| SCHEMBL21725431 | 0.86 | CYP1A1 (0.40) | CYP11B1CYP1A1CYP1B1MEN1KMT2A | |
| SCHEMBL10051309 | 0.86 | CYP11B1 (0.45) | CYP11B1NISCHCYP1A1CYP1B1MEN1 | |
| SCHEMBL21725394 | 0.85 | CYP1A1 (0.41) | CYP11B1NISCHALOX5CYP1A1CYP1B1 | |
| SCHEMBL19650532 | 0.85 | MEN1 (0.42) | CYP11B1NISCHALOX5NT5ECYP1A1 | |
| SCHEMBL21725430 | 0.84 | HTR2C (0.38) | NISCHALOX5MEN1KMT2AMAPT | |
| SCHEMBL19650660 | 0.79 | ADORA2A (0.36) | CYP11B1NISCHALOX5CYP1A1CYP1B1 | |
| SCHEMBL19650624 | 0.78 | ENPP3 (0.36) | CYP11B1NISCHMEN1KMT2AMAPT | |
| SCHEMBL12210961 | 0.78 | HSD17B10 (0.47) | CYP11B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19638082 | 0.77 | CYP11B1 (0.64) | CYP11B1MAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248966-B1 | PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO LTD (JP) | 2022-12-21 | — | — | EP | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |