SCHEMBL19650645

SCHEMBL19650645

c1cc(-c2nc(-c3ccc(-c4ccc(-c5ccc[nH]5)cc4)cc3)cc(-c3cc4ccccc4c4ccccc34)n2)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 4/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 2/20 0.36
PIM1 P11309 1/20 0.35
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
GLA P06280 1/20 0.34
ADORA2A P29274 1/20 0.34
CYP11B1 P15538 1/20 0.33
SERPINE1 P05121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24767420 0.97 MEN1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650544 0.94 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21725399 0.92 MEN1 (0.41) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650632 0.90 ENPP3 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650545 0.89 CYP1A1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21725379 0.89 PIM1 (0.43) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21725416 0.89 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650630 0.87 MEN1 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650575 0.87 ENPP1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19650546 0.87 KDM4E (0.33) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3248966-B1 PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES HODOGAYA CHEMICAL CO LTD (JP) 2022-12-21 EP disclosed
EP-3248966-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-29 EP disclosed