Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650545 | 0.94 | CYP1A1 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL21725416 | 0.94 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650645 | 0.92 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL24767420 | 0.91 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650660 | 0.89 | ADORA2A (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650638 | 0.89 | ADORA2A (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650632 | 0.86 | ENPP3 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650544 | 0.86 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650618 | 0.86 | ADORA2A (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19650630 | 0.85 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | TYMS, TYMP, DPYD | MEN1 4184/4885KMT2A 3609/4885ALDH1A1 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.