SCHEMBL196518

SCHEMBL196518

O=C(c1ccc(Cl)cc1)C1CCCCC1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.62
MGLL Q99685 7/20 0.62
LMNA P02545 2/20 0.61
ALDH1A1 P00352 1/20 0.61
HTT P42858 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.55
TP53 P04637 1/20 0.55
MAPT P10636 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KDM2B Q8NHM5 3/20 0.55
CNR1 P21554 1/20 0.54
CNR2 P34972 1/20 0.54
HSD11B1 P28845 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2322628 0.98 MGLL (0.64) SRD5A2MGLLLMNAALDH1A1HTT
SCHEMBL16422900 0.94 MGLL (0.58) SRD5A2MGLLLMNAALDH1A1HTT
(4-Chlorophenyl)(Cyclopropyl)Methanone SCHEMBL392801 0.90 MGLL (0.68) MGLLLMNAKMT2AMEN1TP53
(4-Chlorophenyl)(Cyclopropyl)Methanone SCHEMBL6220062 0.86 MGLL (0.64) MGLLLMNAKMT2AMEN1TP53
SCHEMBL894802 0.82 MGLL (0.60) MGLLLMNAKMT2AMEN1TP53
SCHEMBL894800 0.82 MGLL (0.60) MGLLLMNAKMT2AMEN1TP53
SCHEMBL31107800 0.82 MGLL (0.51) SRD5A2MGLLLMNAALDH1A1HTT
SCHEMBL9136087 0.82 SRD5A2 (0.65) SRD5A2MGLLLMNAALDH1A1HTT
SCHEMBL7486159 0.82 SRD5A2 (0.65) SRD5A2MGLLLMNAALDH1A1HTT
SCHEMBL5460665 0.82 SRD5A2 (0.89) SRD5A2LMNAALDH1A1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117693545-A Organosilicon polymer compound and organosilicon polymer material 国立大学法人大阪大学 2024-03-12 CN disclosed
CN-109369406-B Photocatalytic synthesis method and application of 1-hydroxycyclohexyl phenyl ketone compound 甘肃金盾化工有限责任公司 2021-12-14 CN disclosed
CN-109369406-A A kind of photocatalytic synthesis method of 1- hydroxycyclohexyl phenyl ketone class compound and its application 甘肃金盾化工有限责任公司 2019-02-22 CN disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
EP-2390244-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275780-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMCIAL COMPANY LIMITED 2011-11-10 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
CN-1471506-A Process for producing carbonyl alpha-substituted nitrogen-containing compound 北京英力科技发展有限公司 2004-01-28 CN disclosed
CN-1314906-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-09-26 CN disclosed
EP-1060166-A1 FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS Boehringer Ingelheim Pharma KG (DE) 2000-12-20 EP disclosed
US-6114532-A ANTICOAGULANT BOEHRINGER INGELHEIM PHARMA KG (DE) 2000-09-05 US disclosed
WO-1999040072-A1 FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS BOEHRINGER INGELHEIM PHARMA KG (DE) 1999-08-12 WO disclosed
EP-0049913-B1 NEW ETHENYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; INTERMEDIATES, USEFUL IN THEIR PREPARATION AND A PROCESS FOR THE PREPARATION THEREOF GIST-BROCADES N.V. (NL) 1986-03-19 EP disclosed
EP-0049913-A2 New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof GIST-BROCADES N.V. (NL) 1982-04-21 EP disclosed
US-3956316-A PROGESTATIONAL AND SALT-RETAINING AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-05-11 US disclosed