Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136087 | 1.00 | SRD5A2 (0.65) | SRD5A2MGLLCNR1CNR2MIF | |
| SCHEMBL1334288 | 0.98 | SRD5A2 (0.61) | SRD5A2MGLLCNR1CNR2MIF | |
| SCHEMBL1335827 | 0.94 | SRD5A2 (0.56) | SRD5A2MGLLMIFRAB9ALMNA | |
| SCHEMBL1334195 | 0.89 | MGLL (0.57) | SRD5A2MGLLRAB9ALMNAHTT | |
| SCHEMBL5370523 | 0.89 | MGLL (0.57) | SRD5A2MGLLRAB9ALMNAHTT | |
| SCHEMBL5370517 | 0.89 | MGLL (0.57) | SRD5A2MGLLRAB9ALMNAHTT | |
| Water SCHEMBL6848223 | 0.85 | MGLL (0.54) | SRD5A2MGLLRAB9ALMNAHTT | |
| SCHEMBL5460665 | 0.83 | SRD5A2 (0.89) | SRD5A2RAB9AHRH3LMNAHTT | |
| SCHEMBL3161623 | 0.82 | SRD5A2 (0.62) | SRD5A2MGLLCNR1CNR2RAB9A | |
| SCHEMBL507614 | 0.82 | KMT2A (0.66) | SRD5A2MGLLRAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |
| US-5399698-A | Lipoxygenase inhibitor intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| US-5231103-A | Lipoxygenase inhibitors as antiinflammatory agents, antiasthma and cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0525571-A1 | Quinolin-2-yl-methoxybenzylhydroxyureas as lipoxygenase inhibitors | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |
| US-3979456-A | Phenoxyalkylamines, process for their preparation and applications thereof | LABORATOIRES LAROCHE NAVARRON (FR) | 1976-09-07 | — | — | US | disclosed |