Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 3/20 | 0.48 | |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657526 | 0.95 | HPGD (0.46) | PDFHPGDKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL3932621 | 0.80 | PDF (0.48) | PDFHPGDKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL10036144 | 0.77 | MAPT (0.41) | KDM4EL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL1506902 | 0.76 | MEN1 (0.50) | PDFHPGDKDM4EL3MBTL1MEN1 | |
| SCHEMBL15601772 | 0.75 | MAPT (0.35) | PDFHPGDKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL16640286 | 0.74 | MAPT (0.34) | PDFHPGDKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL3935749 | 0.72 | MEN1 (0.42) | PDFHPGDKDM4EL3MBTL1MEN1 | |
| SCHEMBL28574750 | 0.72 | MEN1 (0.49) | HPGDKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL15186179 | 0.72 | MEN1 (0.49) | HPGDKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL17928441 | 0.72 | MEN1 (0.49) | HPGDKDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340622-A1 | METHOD OF DETECTING CANCER STEM CELL, METHOD OF SCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCER STEM CELL | CANON KK (JP) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340622-A1 | METHOD OF DETECTING CANCER STEM CELL, METHOD OF SCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCER STEM CELL | MKI67, KIT, ALDH1A1 | PDF 4485/4885HPGD 1942/4885KDM4E 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.