Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.82 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | FABP3 | P05413 | 1/20 | 0.65 |
| ▸ | SELP | P16109 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31615945 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31469169 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31515814 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31366836 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31381149 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL236438 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL79578 | 1.00 | ALDH1A1 (0.85) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL23834444 | 0.99 | NR5A2 (0.83) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL234615 | 0.99 | NR5A2 (0.83) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL233018 | 0.99 | NR5A2 (0.83) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220155306-A1 | Biomarkers of Breast and Lung Cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2022-05-19 | — | — | US | claimed |
| WO-2025091079-A1 | DIAGNOSTIC SIGNATURE | BCAL Diagnostics Limited (AU) | 2025-05-08 | — | — | WO | disclosed |
| US-20220155306-A1 | Biomarkers of Breast and Lung Cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2022-05-19 | — | — | US | disclosed |
| US-9957287-B2 | Methods and compositions to treat type-1 and type-2 diabetes | CORNELL UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170342097-A1 | METHODS AND COMPOSITIONS TO TREAT TYPE-1 AND TYPE-2 DIABETES | CORNELL UNIVERSITY | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342097-A1 | METHODS AND COMPOSITIONS TO TREAT TYPE-1 AND TYPE-2 DIABETES | IAPP, GPR119, IRS1 | ALDH1A1 2816/4885NR5A2 1574/4885NR5A1 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.