Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | UBE2M | P61081 | 3/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696343 | 0.84 | CCR5 (0.51) | CCR5UBE2MDCUN1D1SMN1; SMN2 | |
| SCHEMBL26170593 | 0.83 | CACNA1I (0.39) | CCR5UBE2MDCUN1D1OPRM1OPRL1 | |
| SCHEMBL19658644 | 0.81 | SMN1; SMN2 (0.41) | UBE2MDCUN1D1SMN1; SMN2OPRM1EPHX1 | |
| SCHEMBL19652116 | 0.81 | KDM4E (0.36) | CCR5KMT2AL3MBTL1HTR2A | |
| SCHEMBL19658640 | 0.75 | EPHX1 (0.37) | UBE2MDCUN1D1SMN1; SMN2OPRM1TLR9 | |
| SCHEMBL22906377 | 0.75 | EPHX1 (0.39) | CCR5SMN1; SMN2OPRM1EPHX1EPHX2 | |
| SCHEMBL19702056 | 0.75 | ALDH1A1 (0.41) | EPHX1EPHX2L3MBTL1 | |
| SCHEMBL25570811 | 0.74 | CCR5 (0.43) | CCR5UBE2MDCUN1D1OPRM1 | |
| SCHEMBL25568011 | 0.74 | CCR5 (0.48) | CCR5UBE2MDCUN1D1 | |
| SCHEMBL23986483 | 0.73 | CCR5 (0.46) | CCR5UBE2MDCUN1D1SMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | CCR5 1178/4885UBE2M 3401/4885DCUN1D1 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.