Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789291 | 0.85 | TUBB4A (0.43) | ALDH1A1TP53KDM4EHPGDCYP19A1 | |
| SCHEMBL30949067 | 0.81 | HTR2C (0.47) | HPGD | |
| SCHEMBL8788834 | 0.78 | PDE10A (0.35) | GRM5GRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31280170 | 0.78 | NPC1 (0.34) | GRM5GRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27405786 | 0.74 | HTR2C (0.43) | SMN1; SMN2KDM4E | |
| SCHEMBL28098222 | 0.73 | CFTR (0.39) | GRM5GRM1ALDH1A1CFTRHPGD | |
| SCHEMBL29195552 | 0.73 | PDE4D (0.40) | KDM4ECYP19A1 | |
| Hydrochloric Acid SCHEMBL27760920 | 0.73 | HTR2C (0.44) | SMN1; SMN2KDM4E | |
| SCHEMBL22051439 | 0.72 | PKM (0.35) | SMN1; SMN2NPC1RAB9AALDH1A1CFTR | |
| SCHEMBL30473345 | 0.71 | SLC6A4 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017203047-A1 | POLYMERS, PROCESSES, COMPOSITIONS & USES | DSM IP ASSETS B.V. (NL) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017203045-A1 | POLYMERS, PROCESSES, COMPOSITIONS & USES | DSM IP ASSETS B.V. (NL) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017203044-A2 | POLYMERS, PROCESSES, COMPOSITIONS & USES | DSM IP ASSETS B.V. (NL) | 2017-11-30 | — | — | WO | disclosed |