Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19652286 | 0.88 | SLC6A4 (0.49) | ACHE | |
| SCHEMBL19652186 | 0.87 | CXCR4 (0.50) | ACHEBCHE | |
| SCHEMBL19658607 | 0.86 | CXCR4 (0.56) | — | |
| SCHEMBL19652183 | 0.86 | CYP2D6 (0.53) | ACHE | |
| SCHEMBL19658479 | 0.85 | ACHE (0.76) | ACHEBCHE | |
| SCHEMBL19652185 | 0.84 | ATM (0.53) | ACHE | |
| SCHEMBL19658490 | 0.83 | ACHE (0.63) | ACHEBCHE | |
| SCHEMBL19658600 | 0.81 | OPRM1 (0.47) | ACHE | |
| SCHEMBL19652177 | 0.81 | CYP2D6 (0.49) | — | |
| SCHEMBL30110496 | 0.80 | ACHE (0.66) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | ACHE 2649/4885BCHE 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.