SCHEMBL1965267

SCHEMBL1965267

CC(C)(C)OC(=O)N1CCC2(CC1=O)CC2(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.38
BUB1 O43683 1/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
PDE4A P27815 2/20 0.31
PDE4B Q07343 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16409307 0.79 BUB1 (0.42) KDM1ABUB1USP2SMN1; SMN2DDB1
SCHEMBL31480068 0.79 KDM1A (0.41) KDM1ABUB1USP2SMN1; SMN2DDB1
SCHEMBL1966889 0.77
SCHEMBL25316236 0.76 KDM1A (0.38) KDM1ABUB1USP2SMN1; SMN2DDB1
SCHEMBL1966100 0.75 USP2 (0.50) USP2SMN1; SMN2DDB1CRBNMEN1
SCHEMBL25314667 0.75 KDM1A (0.37) KDM1ABUB1USP2SMN1; SMN2DDB1
SCHEMBL25319841 0.74 KDM1A (0.41) KDM1ABUB1USP2SMN1; SMN2CHRM2
SCHEMBL30361911 0.74 KDM1A (0.47) KDM1AHDAC1HDAC6PDE4APDE4B
SCHEMBL13687307 0.73 KDM1A (0.38) KDM1ABUB1USP2SMN1; SMN2CHRM2
SCHEMBL31480399 0.72 CYP11B2 (0.38) KDM1AUSP2SMN1; SMN2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102137841-B Ortho-substituted haloalkylsulfonanilide derivative and herbicide NISSAN CHEMICAL IND LTD 2014-05-14 CN disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed