Sugi Predict

Sugi Predict / Compounds / SCHEMBL19652913

SCHEMBL19652913

SCHEMBL19652913

c1ccc(-c2ccc(-n3c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cccc(-c6ccccc6)c5)cc4c4cc5oc6ccccc6c5cc43)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ ATM Q13315 1/20 0.42
▸ PLA2G2A P14555 4/20 0.36
▸ PLA2G4A P47712 4/20 0.36
▸ PLA2G10 O15496 1/20 0.35
▸ AHR P35869 2/20 0.35
▸ TSPO P30536 1/20 0.34
▸ HDAC4 P56524 1/20 0.34
▸ MMP12 P39900 1/20 0.33
▸ MMP13 P45452 1/20 0.33
▸ EDNRB P24530 1/20 0.33
▸ EDNRA P25101 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ KMT2A Q03164 4/20 0.32
▸ IL1R1 P14778 1/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ MAPT P10636 3/20 0.32
▸ HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17759721 1.00 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL15583111 1.00 KDM4E (0.42) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19652887 0.99 KDM4E (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19653484 0.99 KDM4E (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19653658 0.98 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL17245987 0.98 KDM4E (0.44) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL24676611 0.96 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL24676085 0.96 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL19653464 0.96 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL24676101 0.96 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2021-09-28 — — US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 — — US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same SOD1, TERT, TELO2 KDM4E 2736/4885L3MBTL1 59/4885ATM 3138/4885
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 KDM4E 2915/4885L3MBTL1 37/4885ATM 3046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.