SCHEMBL19654012

SCHEMBL19654012

c1ccc(-c2ccc(-c3nc(-c4cccc(-n5c6ccccc6c6c7c8ccccc8n(-c8ccccc8)c7ccc65)c4)nc4ccccc34)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ATM Q13315 2/20 0.47
WHR1 P49842 1/20 0.39
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NUDT1 P36639 3/20 0.37
ADORA2A P29274 1/20 0.37
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ABCG2 Q9UNQ0 4/20 0.36
GAA P10253 2/20 0.36
PDE10A Q9Y233 1/20 0.35
NR1I3 Q14994 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
VDR P11473 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653989 0.99 MEN1 (0.46) MEN1KMT2AATMWHR1KDM4E
SCHEMBL19653988 0.98 MEN1 (0.46) MEN1KMT2AATMWHR1KDM4E
SCHEMBL20152144 0.97 ATM (0.49) MEN1KMT2AATMWHR1KDM4E
SCHEMBL19653973 0.96 MEN1 (0.45) MEN1KMT2AATMWHR1KDM4E
SCHEMBL20152145 0.96 MEN1 (0.47) MEN1KMT2AATMWHR1KDM4E
SCHEMBL23370462 0.95 MEN1 (0.48) MEN1KMT2AATMWHR1KDM4E
SCHEMBL20315807 0.95 MEN1 (0.48) MEN1KMT2AATMWHR1KDM4E
SCHEMBL19654008 0.95 MEN1 (0.44) MEN1KMT2AATMWHR1KDM4E
SCHEMBL20226355 0.94 MEN1 (0.44) MEN1KMT2AATMWHR1KDM4E
SCHEMBL19653969 0.94 MEN1 (0.43) MEN1KMT2AATMWHR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230292539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
EP-4231804-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-08-23 EP disclosed
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-24 US disclosed
US-10985328-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-20 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSGEP MEN1 2315/4885KMT2A 3477/4885ATM 2960/4885
US-10985328-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR MEN1 3265/4885KMT2A 1235/4885ATM 1995/4885
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR MEN1 3265/4885KMT2A 1235/4885ATM 1995/4885
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR MEN1 3265/4885KMT2A 1235/4885ATM 1995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.