Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 5/20 | 0.79 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.58 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.46 |
| ▸ | BMX | P51813 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19654244 | 0.91 | ULK1 (0.66) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL19654239 | 0.89 | ULK1 (0.63) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL19654246 | 0.89 | ULK1 (0.64) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL17544722 | 0.88 | ULK1 (1.00) | ULK1PRKAA2PRKAA1ULK2PTK2 | |
| SCHEMBL19654242 | 0.86 | ULK1 (0.60) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL19654236 | 0.85 | ULK1 (0.75) | ULK1PRKAA2PRKAA1ULK2PTK2 | |
| SCHEMBL19654241 | 0.84 | ULK1 (0.58) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL19654250 | 0.82 | ULK1 (0.56) | ULK1PRKAA2PRKAA1ULK2PKMYT1 | |
| SCHEMBL19654240 | 0.82 | ULK1 (0.59) | ULK1PRKAA2PRKAA1ULK2PTK2 | |
| SCHEMBL19654252 | 0.82 | ULK1 (0.55) | ULK1PRKAA2PRKAA1ULK2BMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342088-A1 | NOVEL ULK1 INHIBITORS AND METHODS USING SAME | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342088-A1 | NOVEL ULK1 INHIBITORS AND METHODS USING SAME | ULK1, ULK2, ULK3 | ULK1 1/4885PRKAA2 181/4885PRKAA1 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.