Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488537 | 0.86 | — | — | |
| SCHEMBL25880206 | 0.82 | LMNA (0.31) | KDM4E | |
| SCHEMBL1966308 | 0.81 | GLA (0.38) | AOC2 | |
| SCHEMBL20742723 | 0.75 | KDM4E (0.39) | KDM4E | |
| SCHEMBL1192425 | 0.73 | EPHX1 (0.32) | AOC2 | |
| SCHEMBL1439821 | 0.73 | AOC2 (0.35) | AOC2 | |
| Hydrochloric Acid SCHEMBL16761535 | 0.71 | AOC2 (0.34) | AOC2 | |
| SCHEMBL15774425 | 0.71 | KDM4E (0.39) | KDM4E | |
| SCHEMBL1968142 | 0.71 | KDM4E (0.43) | KDM4E | |
| SCHEMBL3831648 | 0.70 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334657-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. Hoffmann-La Roche AG (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010031735-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |