SCHEMBL19655313

SCHEMBL19655313

c1ccc(-c2nc3ccccc3nc2-c2cccc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc4c3oc3ccccc34)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
KDM4E B2RXH2 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
ATM Q13315 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
MAPT P10636 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HSD17B10 Q99714 2/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
TP53 P04637 2/20 0.32
PTGER1 P34995 1/20 0.32
ALDH1A1 P00352 2/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653922 0.91 MEN1 (0.33) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL19655199 0.91 MEN1 (0.35) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL19655312 0.89 PDE10A (0.33) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL19655289 0.88 HSD17B10 (0.36) MEN1KMT2AKDM4ECSF1RPDGFRB
SCHEMBL24356507 0.87 KDM4E (0.40) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL19655316 0.87 KDM4E (0.35) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL24230619 0.86 KDM4E (0.39) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL23072404 0.86 KDM4E (0.39) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL18868289 0.85 KDM4E (0.34) MEN1KMT2AKDM4EL3MBTL1ATM
SCHEMBL21716827 0.85 ALOX5 (0.33) KDM4ETP53ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885KDM4E 2543/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885KDM4E 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.