SCHEMBL19655314

SCHEMBL19655314

c1ccc(-c2ccc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc(-c4nc5ccccc5nc4-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.45
KDM4E B2RXH2 3/20 0.45
ATM Q13315 1/20 0.45
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 3/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
THRB P10828 1/20 0.40
DHODH Q02127 2/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
PDE10A Q9Y233 1/20 0.37
MAPT P10636 2/20 0.37
HSP90AA1 P07900 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
IL1R1 P14778 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655307 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655405 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655308 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655319 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655311 0.95 L3MBTL1 (0.44) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655330 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655329 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL20886601 0.94 L3MBTL1 (0.51) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL11987940 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL19655310 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.