SCHEMBL19655372

SCHEMBL19655372

c1ccc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4cccc(-c5cnc6c7ccccc7c7ccccc7c6n5)c4)cc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
MAT2A P31153 1/20 0.32
MAPT P10636 3/20 0.31
KMT2A Q03164 3/20 0.31
IL1R1 P14778 1/20 0.31
NPC1 O15118 1/20 0.31
PDGFRB P09619 1/20 0.31
KDR P35968 1/20 0.31
FLT3 P36888 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 2/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
RAC2 P15153 1/20 0.30
RAC3 P60763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655359 0.97 L3MBTL1 (0.43) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL19655363 0.96 L3MBTL1 (0.40) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL19655257 0.94 KDM4E (0.38) L3MBTL1KDM4EATMMAT2AMAPT
SCHEMBL19655362 0.93 KDM4E (0.39) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL17464151 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL17456843 0.91 KDM4E (0.38) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL30150711 0.91 KDM4E (0.38) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL17464142 0.91 KDM4E (0.38) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL30150704 0.91 KDM4E (0.38) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL19655364 0.91 KDM4E (0.37) L3MBTL1KDM4EATMMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.