SCHEMBL19655404

SCHEMBL19655404

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc(-c4nc5c6ccccc6c6ccccc6c5nc4-c4ccccc4)c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.37
KDM4E B2RXH2 4/20 0.37
ATM Q13315 1/20 0.37
MAPT P10636 3/20 0.31
MAPK1 P28482 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 2/20 0.30
USP2 O75604 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655360 0.90 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL19655383 0.87 L3MBTL1 (0.45) L3MBTL1KDM4EATMMAPTMEN1
SCHEMBL23370353 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL12268602 0.87 L3MBTL1 (0.49) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL23072408 0.86 L3MBTL1 (0.42) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL16303002 0.85 L3MBTL1 (0.40) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL12268763 0.84 L3MBTL1 (0.46) L3MBTL1KDM4EATMMAPTMEN1
SCHEMBL257173 0.84 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL26059808 0.82 MEN1 (0.42) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL26059881 0.82 MEN1 (0.44) L3MBTL1KDM4EATMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.