SCHEMBL19655448

SCHEMBL19655448

Cc1sc(C)c(SCCSc2cccnc2)c1SCCSc1cccnc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GRM2 Q14416 1/20 0.37
TYMS P04818 1/20 0.37
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2D6 P10635 3/20 0.36
CYP2C9 P11712 3/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2A6 P11509 2/20 0.36
CYP3A4 P08684 2/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
CYP2E1 P05181 1/20 0.35
CYP2B6 P20813 1/20 0.35
GRM5 P41594 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655451 0.80 ALDH1A1 (0.60) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL19662731 0.80 NPC1 (0.50) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL7870609 0.77 L3MBTL1 (0.45) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL31403119 0.75 ALDH1A1 (0.44) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL28037041 0.74 MAPT (0.55) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL4684825 0.73 ALDH1A1 (0.45) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL28072922 0.73 HTT (0.50) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL12796842 0.73 CHRNA7 (0.47) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL4207994 0.73 ALDH1A1 (0.42) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL4684826 0.73 MAPK1 (0.47) NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9991518-B2 Polythiophene derivative, method for producing same, positive electrode active material for secondary batteries, and secondary battery RICOH COMPANY, LTD. (JP) 2018-06-05 US disclosed
US-20170346095-A1 POLYTHIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, POSITIVE ELECTRODE ACTIVE MATERIAL FOR SECONDARY BATTERIES, AND SECONDARY BATTERY RICOH COMPANY, LTD. (JP) 2017-11-30 US disclosed