Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657007 | 1.00 | ADORA1 (0.48) | ADORA1ADORA3ADORA2AADORA2BPOLB | |
| SCHEMBL22931042 | 0.98 | ADORA1 (0.49) | ADORA1ADORA3ADORA2AADORA2BPOLB | |
| SCHEMBL242610 | 0.94 | ADORA1 (0.52) | ADORA1ADORA3ADORA2AADORA2BPOLB | |
| SCHEMBL4670822 | 0.80 | ADORA3 (0.40) | ADORA1ADORA3ADORA2AADORA2BNPC1 | |
| SCHEMBL312409 | 0.80 | SLC18A3 (0.50) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8016614 | 0.79 | KDM4E (0.44) | ADORA1ADORA3ADORA2AADORA2BDHODH | |
| Hydrochloric Acid SCHEMBL1653372 | 0.79 | SLC18A3 (0.49) | ADORA1ADORA3ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL311386 | 0.79 | SLC18A3 (0.49) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6166041 | 0.78 | SLC18A3 (0.47) | ADORA1ADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL6806273 | 0.77 | SLC18A3 (0.46) | ADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10314820-B2 | Imidazole-based heterocyclic compounds | PROCOMCURE BIOTECH GMBH (AT) | 2019-06-11 | — | — | US | disclosed |
| US-20170340613-A1 | Novel Imidazole-Based Heterocyclic Compounds | PROCOMCURE BIOTECH GMBH (AT) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340613-A1 | Novel Imidazole-Based Heterocyclic Compounds | SLC11A2, MIF, NISCH | ADORA1 2789/4885ADORA3 3271/4885ADORA2A 3561/4885 |
| US-10314820-B2 | Imidazole-based heterocyclic compounds | MIF, SLC11A2, TLR5 | ADORA1 2636/4885ADORA3 3026/4885ADORA2A 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.